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Hair Regrowth Steroid Hormones 98319-26-7 , White Powder Finasteride For Male Sex Hormones

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Shanghai Poochun Industry Co.,Ltd
City: Shanghai
Province/State: Shanghai
Country/Region: China

Hair Regrowth Steroid Hormones 98319-26-7 , White Powder Finasteride For Male Sex Hormones

Brand Name : PooChun
Model Number : CAS 98319-26-7
Certification : ISO9001 SGS HACCP
Place of Origin : China
MOQ : Negotiable
Price : Negotiable
Payment Terms : T/T, L/C, Western Union, MoneyGram
Supply Ability : 100 ton per Month
Delivery Time : 1-3days after payment
Packaging Details : 1~10 kg / Al-Pt bag,10kg / 25kg fiber drum
CAS : 98319-26-7
Appearance : White powder
MF : C23H36N2O2
MW : 372.549
Trade terms : FOB CNF CIF DAP DDU
Shipping : DHL TNT FedEx HKEMS UPS
Payment terms : T/T, Western Union, Paypal, Moneygram
Type : 4 - nitrogen heterosteroidal compounds
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Steroid Hormones Medicine Raw Material Finasteride For Male Sex Hormones Propecia Hair Regrowth



Description


Finasteride, sold under the brand names Proscar and Propecia among others, is a medication used for the treatment of benign prostatic hyperplasia ( enlarged prostate ) and male pattern hair loss. It is a type II and type III 5α - reductase inhibitor; 5α - reductase, an enzyme, converts testosterone to dihydrotestosterone ( DHT ).


Medical uses


1. Prostate enlargement


Physicians sometimes use finasteride for the treatment of BPH, informally known as an enlarged prostate. Finasteride may improve the symptoms associated with BPH such as difficulty urinating, getting up during the night to urinate, hesitation at the start of urination, and decreased urinary flow. It provides less symptomatic relief than alpha -1 blockers such as tamsulosin and symptomatic relief is slower in onset ( six months or more of treatment with finasteride may be required to determine the therapeutic results of treatment ). Symptomatic benefits are mainly seen in those with prostate volume > 40 cm3. In long - term studies finasteride but not alpha-1 inhibitors reduce the risk of acute urinary retention ( −57% at 4 years ) and the need for surgery ( −54% at 4 years ). If the drug is discontinued, any therapeutic benefits reverse within about 6–8 months.


2. Pattern hair loss


Finasteride is sometimes used to treat pattern hair loss ( androgenetic alopecia ) in men only. Treatment slows further hair loss and provides about 30% improvement in hair loss after six months of treatment, with effectiveness usually only persisting as long as the drug is taken, although on occasion hair loss is slowed indefinitely following withdrawal. Finasteride has also been tested for pattern hair loss in women; the results were no better than placebo.


3. Excessive hair growth


Finasteride has been found to be effective in the treatment of hirsutism ( excessive facial and/or body hair growth ) in women. In a study of 89 women with hyperandrogenism due to persistent adrenarche syndrome, finasteride produced a 93% reduction in facial hirsutism and a 73% reduction bodily hirsutism after 2 years of treatment. Other studies using finasteride for hirsutism have also found it to be clearly effective.


4. Transgender women


Finasteride is sometimes used in hormone replacement therapy for transgender women due to its antiandrogen properties, in combination with a form of estrogen. However, little clinical research of finasteride use for this purpose has been conducted and evidence of efficacy is limited. Moreover, caution has been recommended when prescribing finasteride to transgender women, as finasteride may be associated with side effects such as depression, anxiety, and suicidal ideation, symptoms that are particularly prevalent in the transgender population and in others at high risk already.


Specification


Test ItemsSpecificationTest Results
DescriptionWhite or off-white crystalline powderOff-white crystalline powder
Specific rotation-56°~-60°-58.2°
IdentificationIRMatches with working standardComplies
HPLC
SolubilityFreely soluble in chloroform and in alcohol;
Very slightly soluble in water
Conform
Heavy metals≤10ppm<10ppm
Water≤0.3%0.22%
Residue on ignition≤0.1%0.05%
Relative materialMaximum impurities≤0.5%0.36%
Total impurities≤1.0%0.52%
Assay98.5~101.0%99.59%
ConclusionThe specification conform with Enterprise standard


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pharmaceutical intermediates

      

pharmaceutical raw materials

      
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Hair Regrowth Steroid Hormones 98319-26-7 , White Powder Finasteride For Male Sex Hormones Images

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